Application · LNP Characterization

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See what's actually inside every LNP batch.

One read for particle size, encapsulation efficiency, and lipid chemical integrity for batches other instruments can't reach.

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BUILT FORFormulation Scientists · Analytical Development · R&D and QC teams running mRNA-LNP programs

What This Application Is Really Asking

Lipid nanoparticles (LNPs) are the delivery vehicles behind mRNA therapeutics and vaccines, consisting of a lipid shell built to carry a nucleic-acid payload. Three things decide whether a batch is good: particle uniformity, how much payload made it inside vs. floating free, and whether the lipid shell remains chemically intact. Most instruments answer only one or two well, but RIPPLE aims to answer all three from a single measurement and even with early-stage samples.

Key Parameters

What Makes RIPPLE Unique

• 1
  One read, three answers  Size, EE%, and lipid chemical integrity come out of the same measurement instead of having to maintain separate assay pipelines.
• 2
  Reaches earlier-stage batches  RIPPLE’s 1 ng/mL concentration floor means very early, low-yield microfluidic formulations don't have to wait for scale-up.
• 3
  One read, under a minute  RIPPLE’s technology makes a measurement in ~60-second reads, meaning triage can be done extremely fast on a high number of samples.